Sweeteners in food samples: An update on pretreatment and analysis techniques since 2015.

This study focuses on sweeteners in food samples: an update on pretreatment and analysis techniques since 2015.. The research employs high-performance liquid chromatography (HPLC) techniques to address analytical challenges in the food safety field. Sweeteners play an irreplaceable role in daily life and have been found in multitudinous food products. However, excessive or unreasonable intake of sweeteners as food additives brings about untoward problems due to the accumulation in the human body. Therefore, a comprehensive review of different sweeteners' pretreatment and determination methods is... Research Background and Significance Sweeteners have become ubiquitous additives in the global food industry due to their ability to provide sweetness without the caloric impact of sugar. Since 2015, the growing diversity of natural and artificial sweeteners, alongside increasing regulatory scrutiny and consumer demand for safety, has necessitated advanced analytical techniques to accurately quantify these compounds in complex food matrices. Excessive or inappropriate consumption of sweeteners can lead to health concerns, including metabolic disruptions and long-term bioaccumulation effects. Therefore, the precise detection and quantification of sweeteners in food samples underpin food safety monitoring and regulatory compliance. This study by Chen et al. (2023) addresses these critical needs by updating pretreatment and analysis techniques, focusing on the application of high-performance liquid chromatography (HPLC) methods. The review consolidates recent advancements in sample preparation and chromatographic approaches, underscoring the importance of robust, sensitive, and reliable analytical workflows for sweetener determination. Experimental Design and Methodology The stu