Speciation analysis of arsenic in honey using HPLC-ICP-MS and health risk assessment of water-soluble arsenic.

This study focuses on speciation analysis of arsenic in honey using hplc-icp-ms and health risk assessment of water-soluble arsenic.. The research employs high-performance liquid chromatography (HPLC) techniques to address analytical challenges in the environmental field. It is well known that arsenic is one of the most toxic elements. However, measuring total arsenic content is not enough, as it occurs in various forms that vary in toxicity. Since honey can be used as a bioindicator of environmental pollution, in the present study the concentration of arsenic... Research Background and Significance Arsenic is a well-known toxic element, prevalent in various environmental matrices due to both natural processes and anthropogenic activities. Its toxicity, however, is highly dependent on its chemical form or speciation rather than total concentration alone. This distinction is crucial because inorganic arsenic species (As(III) and As(V)) are generally more toxic than organic forms such as arsenobetaine or arsenosugars. Honey, produced by bees collecting nectar from diverse floral sources, can accumulate environmental contaminants including arsenic, making it a valuable bioindicator for environmental monitoring. Given the health implications of arsenic exposure, especially via food products, accurate speciation analysis is essential to evaluate potential risks. The study by Jakkielska et al. (2024) addresses this critical need by employing high-performance liquid chromatography coupled with inductively coupled plasma mass spectrometry (HPLC-ICP-MS) to quantify and speciate water-soluble arsenic in honey. This approach provides a sensitive, selective, and reliable method for environmental and food safety assessments, facilitating comprehensive health risk evaluations. Experi