Simultaneous analysis of antimicrobial residues and contaminants in poultry droppings by HPLC-MS/MS: a tool for environmental and food safety monitoring.

This study focuses on simultaneous analysis of antimicrobial residues and contaminants in poultry droppings by hplc-ms/ms: a tool for environmental and food safety monitoring.. The research employs high-performance liquid chromatography (HPLC) techniques to address analytical challenges in the environmental field. Animal waste is a potential pollution hazard as it can harbour contaminants, such as antimicrobial residues, mycotoxins, and pesticides, becoming a risk to the public, animal, and environmental health. To assess this risk, 15 experimental broiler chickens orally received contaminants to evaluate excretion levels. An analytical method was previously developed... Research Background and Significance The presence of antimicrobial residues and various contaminants in animal waste, especially poultry droppings, poses a significant environmental and public health concern. Poultry farming is widespread globally, and the use of veterinary drugs such as antimicrobials is common for disease prevention and growth promotion. However, these substances can persist in animal waste, potentially contaminating soil and water bodies and contributing to antimicrobial resistance. Additionally, other contaminants like mycotoxins and pesticides may also co-exist in these droppings, further complicating environmental safety. This study by Trincado et al. (2024) addresses the urgent need for reliable analytical methods capable of simultaneously detecting multiple classes of residues and contaminants in poultry droppings. Employing high-performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS/MS) enables high sensitivity, specificity, and throughput, making it a powerful tool for comprehensive environmental monitoring. The research provides a foundation for impr