Screening and Identification of Croton Fruit Poisoning in Food Using GC-MS and HPLC-MS/MS.

This study focuses on screening and identification of croton fruit poisoning in food using gc-ms and hplc-ms/ms.. The research employs high-performance liquid chromatography (HPLC) techniques to address analytical challenges in the food safety field. Croton fruit poisoning was successfully identified through a series of chromatographic technologies. A suspected compound named 2-methyl-butenoic acid was screened out using gas chromatography-mass spectrometry, and the hydrolysate of isoguanosine in soup sample was further detected by high performance liquid chromatography-tandem mass spectrometry. The identification of croton fruit poisoning was... Research Background and Significance Food safety remains a critical global concern, with the detection of toxic contaminants in food products being paramount for public health protection. Croton fruit, known for its toxic properties, poses a significant risk when accidentally incorporated into food items, leading to poisoning incidents. Traditional detection methods often lack the sensitivity and specificity required to accurately identify toxic compounds in complex food matrices. The study by Chen et al. (2022) addresses this analytical challenge by integrating gas chromatography-mass spectrometry (GC-MS) and high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) techniques to effectively screen and identify croton fruit poisoning. This dual-analytical approach leverages the strengths of both chromatographic methods, enhancing the reliability of toxin detection in food safety applications. Experimental Design and Methodology The study employed a systematic approach combining GC-MS and HPLC-MS/MS to detect and confirm toxic compounds associated with croton fruit poisoning in food samples. Initially, GC-MS