Extraction of natural products using supercritical fluids and pressurized liquids assisted by ultrasound: Current status and trends.

This study focuses on extraction of natural products using supercritical fluids and pressurized liquids assisted by ultrasound: current status and trends.. The research employs high-performance liquid chromatography (HPLC) techniques to address analytical challenges in the chemical field. Natural products are a source of a wide range of chemical compounds, from pigments to bioactive compounds, which can be extracted and used in different applications. Due to consumer awareness, the interest in natural compounds significantly increased in the last decades, prompting the search for more efficient and environmentally friendly...

This study focuses on extraction of natural products using supercritical fluids and pressurized liquids assisted by ultrasound: current status and trends.. The research employs high-performance liquid chromatography (HPLC) techniques to address analytical challenges in the chemical field. Natural products are a source of a wide range of chemical compounds, from pigments to bioactive compounds, which can be extracted and used in different applications. Due to consumer awareness, the interest in natural compounds significantly increased in the last decades, prompting the search for more efficient and environmentally friendly... Research Background and Significance The extraction of natural products has become increasingly significant due to heightened consumer demand for bioactive compounds and natural ingredients in pharmaceuticals, nutraceuticals, cosmetics, and food industries. Traditional extraction methods, often solvent-intensive and time-consuming, have limitations regarding efficiency and environmental impact. Supercritical fluid extraction (SFE) and pressurized liquid extraction (PLE) have emerged as advanced techniques offering enhanced extraction yields, selectivity, and reduced solvent usage. When combined with ultrasound assistance, these techniques exploit acoustic cavitation to disrupt plant matrices and improve mass transfer, resulting in faster and more efficient extraction processes. The study by Dias et al. (2021) critically evaluates these extraction methods with a focus on integrating ultrasound to optimize the recovery of bioactive natural products. High-performance liquid chromatography (HPLC) plays a pivotal role in this research, providing robust analytical capabilities to characterize and quantify the extracted compounds, ensuring reproducibility