Extraction and detection of morin from Sanghuangporus lonicericola by magnetic molecularly imprinted polymers coupled with HPLC analysis.

This study focuses on extraction and detection of morin from sanghuangporus lonicericola by magnetic molecularly imprinted polymers coupled with hplc analysis.. The research employs high-performance liquid chromatography (HPLC) techniques to address analytical challenges in the environmental field. In this study, morin magnetic molecularly imprinted polymers (Morin-MMIPs) were synthesized based on magnetic nanoparticles and surface molecularly imprinted technology with superparamagnetism and extraction selectivity. The polymers allowed the separating of morin from complex matrices in the presence of an external magnetic field with no need for centrifugation or filtration.... Research Background and Significance Morin is a bioactive flavonoid compound with significant pharmacological properties, including antioxidant, anti-inflammatory, and anticancer effects. Extracting and detecting morin from natural sources is critical for environmental and pharmaceutical research, particularly when dealing with complex biological matrices such as fungi. Sanghuangporus lonicericola, a medicinal fungus, contains morin at trace levels, making its selective extraction challenging. Traditional extraction methods often require extensive sample preparation, including centrifugation and filtration, which are time-consuming and may lead to analyte loss. This study addresses these challenges by employing magnetic molecularly imprinted polymers (Morin-MMIPs) combined with high-performance liquid chromatography (HPLC) to achieve selective extraction and sensitive detection of morin. The integration of magnetic separation with molecular imprinting technology offers a novel approach for rapid, efficient, and selective isolation of morin, facilitating its accurate quantification in complex environ